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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CNOT3 All Species: 10.61
Human Site: S491 Identified Species: 23.33
UniProt: O75175 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75175 NP_055331.1 753 81872 S491 A P G S G N N S G G P S L L V
Chimpanzee Pan troglodytes XP_512885 688 76993 S429 P P S S P T P S F S D A K A A
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_541428 752 81536 T491 A P G S G N N T G G P S L L V
Cat Felis silvestris
Mouse Mus musculus Q8K0V4 751 81927 G491 G S G N N S G G P S L L V P L
Rat Rattus norvegicus NP_001100941 751 81862 G491 G S G N N S G G P S L L V P L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001086992 728 81088 S466 P A N N S S T S T G S S L L L
Zebra Danio Brachydanio rerio NP_956134 908 96903 S491 A I G T N I S S T N S S G V V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610176 844 92349 A495 T P T I A F A A V A K H N T S
Honey Bee Apis mellifera XP_395261 684 76726 N425 H V L H N Q Q N Q N H S S E T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001203995 878 98224 Q491 G G Q T H N S Q G P N P V A N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P06102 836 94385 N492 G A A A V H Q N N Q A F Y R N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 87.9 N.A. 96.6 N.A. 95.2 95.4 N.A. N.A. N.A. 77.1 54.2 N.A. 41.5 51.9 N.A. 45.3
Protein Similarity: 100 88.1 N.A. 97.6 N.A. 96.4 96.6 N.A. N.A. N.A. 84 63.9 N.A. 57.7 65.7 N.A. 58.5
P-Site Identity: 100 20 N.A. 93.3 N.A. 6.6 6.6 N.A. N.A. N.A. 33.3 33.3 N.A. 6.6 6.6 N.A. 13.3
P-Site Similarity: 100 26.6 N.A. 100 N.A. 33.3 33.3 N.A. N.A. N.A. 53.3 53.3 N.A. 13.3 13.3 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 39.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 28 19 10 10 10 0 10 10 0 10 10 10 0 19 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % E
% Phe: 0 0 0 0 0 10 0 0 10 0 0 10 0 0 0 % F
% Gly: 37 10 46 0 19 0 19 19 28 28 0 0 10 0 0 % G
% His: 10 0 0 10 10 10 0 0 0 0 10 10 0 0 0 % H
% Ile: 0 10 0 10 0 10 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 10 0 10 0 0 % K
% Leu: 0 0 10 0 0 0 0 0 0 0 19 19 28 28 28 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 10 28 37 28 19 19 10 19 10 0 10 0 19 % N
% Pro: 19 37 0 0 10 0 10 0 19 10 19 10 0 19 0 % P
% Gln: 0 0 10 0 0 10 19 10 10 10 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % R
% Ser: 0 19 10 28 10 28 19 37 0 28 19 46 10 0 10 % S
% Thr: 10 0 10 19 0 10 10 10 19 0 0 0 0 10 10 % T
% Val: 0 10 0 0 10 0 0 0 10 0 0 0 28 10 28 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _